You and actually look up on a web site (a view from my seat ) what your sight lines would be. As others have said the sight lines in that theater are all good.

Tier 2 center is OK and more economical. Acoustics are very good everywhere in the big theater. Agree that if you want to see the performer(s) you should bring opera glasses or similar. BTW, with lectures and "conversations" there's screen showing the participants so it's not a problem. They don't generally use the screen for musical performances - but you can call and ask.

The sound is perfect and generally natural

Yes, take PATH to Newark. Then you have two or three long blocks to walk.

It would depend on the venue event that you are going to see.

I have been seated all over that theater, and all seats were good seats

Don't go any higher than tier 1, I personally only do box seat depending on what your going to see grand tier is good but if it's a concert not so good as people stand in front of you and you can't see when they do.

I would never purchase tier 4 seats

I don't recommend these seats for small children.

Maize Restaurant in the Robert Treat Hotel about a block away from NJPAC is quite good and reasonably priced. Park first and walk the short distance from the restaurant to NJPAC after your meal, and walk back to parking after the show.